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What are the problems with synthetic estrogen replacement?

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What are the problems with synthetic estrogen replacement?

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When first developed, synthetic estrogens were well received because they offered the benefits of estrogen replacement fighting osteoporosis and heart disease, They also helped to reduce the symptoms associated with menopause. However, the long term results have shown that these synthetics were also eliciting a metabolic response that was not obvious at the start. in some patients, synthetic estrogens contributed to the development of breast and uterine cancer. There are receptor sites in the body that receive messages from hormones, These receptor sites arc being tricked by synthetic hormones into producing a nearly identical result to a natural hormone. However, these receptor sites, when stimulated by synthetic hormones, have, evidently, in the long-.run, produced other, unacceptable results in some patients leading to cancer. A natural hormone does not try to trick the receptor site it acts as an identical hormone replacement.

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