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What are the problems of chronic HBV infection?

April 26, 2017chronic hbsag HBV infection problems viral hepatitis

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What are the problems of chronic HBV infection?

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Chronic HBV carriers have hundred fold increased risk of developing hepatocellular carcinoma .They also may develop chronic liver disease with cirrhosis and liver cell failure. Chronic liver disease in these patients can’t be predicted. Is there any treatment for chronic HBV infection? Alpha interferon and Lamivudine are two agents used currently but experience in children is limited. Can Hepatitis B be prevented? Yes, IAP and WHO recommend universal immunisation with Hepatitis B vaccine which gives 95-98% protection. Currently the recombinant DNA vaccine is used universally in the dosage schedule of 0 , 1 and 6 months starting as early in life as possible . A booster is given after 10 years.