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What are the problems in treatment with second line drugs?

April 26, 2017drugs line problems treatment

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What are the problems in treatment with second line drugs?

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Ans: (i) These drugs are less efficacious and more toxic. (ii) They possess cross resistance to first line drugs (iii) Most patients needing such treatment are difficult to hold e.g. alcoholics, drug addicts, migrants etc, (iv) Hospitalization is a must for observation and regularizing treatment. Ambulatory treatment is possible only after tolerance and regularity assured. (v) It is irrational for any country to divert resources to treating with second line drugs until full potential of SCC regimen has been achieved. Requirement of the reserve drugs indicates poor program.