What are the potential drawbacks of Windows Vista x64 Edition?
A 64-bit Windows operating system is not necessarily faster than its 32-bit counterpart. It may even perform slower because of the larger pointers and unrelated OS overhead. If your application does not involve large-scale data analysis or high-performance float-point calculation or database, you should carefully consider the need to migrate to Windows Vista x64 Edition. Not every application stands to benefit from the x64 architecture as it will take time for Windows Vista x64 Edition to gain widespread adoption.