What are the possible side effects of White horehound (Marrubium vulgare Labiatae)?
White horehound is generally considered to be safe when used as a flavoring agent in foods. However, there is limited scientific study of safety, and most available information is from animal (not human) research. Reported side effects include rash at areas of direct contact with white horehound plant juice, abnormal heart rhythms, low blood pressure, and decreased blood sugar (seen in animals with high blood sugar). White horehound may cause vomiting and diarrhea. Caution is warranted in people with heart disease or gastrointestinal disorders. Caution may also advisable in persons with diabetes or hypoglycemia, and in those taking drugs, herbs, or supplements that affect blood sugar. Serum glucose levels may need to be monitored by a healthcare professional, and medication adjustments may be necessary. Theoretically, white horehound may interfere with the body’s response to the hormone aldosterone, which affects the ability of the kidneys to control the body’s levels of water and elec