What are the possible side effects of Vitamin C (Ascorbic Acid)?
Vitamin C is generally regarded as safe in amounts obtained from foods. Vitamin C supplements are also generally regarded as safe in most individuals in recommended amounts, although side effects are rarely reported including nausea, vomiting, heartburn, abdominal cramps, and headache. Dental erosion may occur from chronically chewing vitamin C tablets. High doses of vitamin C have been associated with multiple adverse effects. These include kidney stones, severe diarrhea, nausea, and gastritis. Rarely, flushing, faintness, dizziness, and fatigue have been noted. Large doses may precipitate hemolysis (red blood cell destruction) in patients with glucose 6-phosphate dehydrogenase deficiency. High doses of vitamin C should be avoided in people with conditions aggravated by acid loading, such as cirrhosis, gout, renal tubular acidosis, or paroxysmal nocturnal hemoglobinuria. Parenteral (injected) vitamin C may cause dizziness, faintness, injection site discomfort, and in high doses may le
