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What are the possible side effects of Reishi mushroom (Ganoderma lucidum)?

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What are the possible side effects of Reishi mushroom (Ganoderma lucidum)?

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Acute and long-term studies have found Ganoderma lucidum to be generally well tolerated in recommended doses for up to 16 months. The most common adverse events reported are skin rash, dizziness and headache. Use cautiously in patients who are taking diabetes/hypoglycemic drugs because reishi may lower blood sugar. Low blood pressure may occur upon utilization of reishi and its derivatives. Due to “blood thinning” capabilities, gastric bleeding could result from the use of reishi. Diarrhea and bloody stools may occur with supplemental doses. Mild gastrointestinal discomfort including nausea and diarrhea has been found in small percentage of cancer patients taking Ganoderma lucidum as Ganopoly®. Reishi may prolong bleeding time and caution is advised in those patients with bleeding disorders (ulcers, hemophilia) or taking anticoagulants.

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