What are the possible side effects of isoniazid and rifampin (Rifamate)?
If you experience any of the following serious side effects, stop taking isoniazid and rifampin and seek emergency medical attention or contact your doctor immediately: • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); • excessive tiredness or weakness; • nausea, vomiting, diarrhea, or loss of appetite; • yellow skin or eyes; • unusual bruising or bleeding; • dark urine; • little or no urine; • numbness or tingling in your hands or feet; • muscle or bone pain; • seizures; • blurred vision; • fever, chills, or a sore throat; • a headache; • a rash or itching; or • confusion or abnormal behavior. Other, less serious side effects may be more likely to occur. Continue to take isoniazid and rifampin and talk to your doctor if you experience • red-orange coloration of tears, sweat, saliva, urine, or feces; or • mild tiredness or weakness. Side effects other than those listed here may also occur. Talk to your doctor about