What are the possible side effects of Folate?
Folate appears to be well tolerated in recommended doses. Stomatitis, alopecia, myelosupression, and zinc depletion have been reported. An intravenous loading dose of folic acid, vitamin B6 and vitamin B12 followed by oral administration of folic acid plus vitamin B6 and vitamin B12, taken daily after coronary stenting, might actually increase restenosis rates. Due to the potential for harm, this combination of vitamins should not be recommended for patients receiving coronary stents. Erythema, pruritus, urticaria, skin flushing, rash, and itching have been reported. Nausea, bloating, flatulence, cramps, bitter taste and diarrhea have been reported. Color of urine may become more intense. Folic acid may mask the symptoms of pernicious, aplastic, or normocytic anemias caused by vitamin B12 deficiency and may lead to neurological damage. Irritability, excitability, general malaise, altered sleep patterns, vivid dreaming, overactivity, confusion, impaired judgment, increased seizure frequ
