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What are the possible side effects of Clove (Eugenia aromatica) and Clove oil (Eugenol)?

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What are the possible side effects of Clove (Eugenia aromatica) and Clove oil (Eugenol)?

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Clove is generally regarded as safe for food use in the United States. However, when clove is taken by mouth in large doses, in its undiluted oil form, or used in clove cigarettes, side effects may occur including vomiting, sore throat, seizure, sedation, difficulty breathing, fluid in the lungs, vomiting of blood, blood disorders, kidney failure, and liver damage or failure. People with kidney or liver disorders or who have had seizures should avoid clove. Serious side effects are reported more often in young children, even with small doses and therefore clove supplements should be avoided in children and pregnant or nursing women. Clove or clove oil may cause an increased bleeding risk, based largely on laboratory research. Caution is advised in patients with bleeding disorders or taking drugs that may increase the risk of bleeding. Dosing adjustments may be necessary. It is not clear what doses or methods of using clove may increase this risk. Liver damage may occur. When applied to

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