What are the possible side effects of amantadine (Symmetrel®) and rimantadine (Flumadine®)?
Side effects of amantadine and rimantadine can include central nervous system (CNS) side effects such as nervousness, anxiety, difficulty concentrating, and lightheadedness, and gastrointestinal side effects like nausea and loss of appetite. CNS side effects happen more often among persons taking amantadine than among persons taking rimantadine. Among some other persons with long-term illnesses, more serious side effects, such as delirium, hallucinations, agitation, and seizures, can occur. Side effects usually diminish and disappear after 1 week. What should be done if possible complications while taking amantadine (Symmetrel®) or rimantadine (Flumadine®) occur? If you experience side effects, talk to your health care provider immediately.