What Are the Phenotypic Effects of Diabetes?
The numerous phenotypic effects of diabetes mellitus have been thoroughly researched and well-documented. Serious complications include retinal damage, poor wound healing, blindness, ketoacidosis, cardiovascular disease, chronic renal failure and microvascular damage. Although diabetes presents various phenotypes, two distinct phenotypes have been identified–MIDD1 and MIDD2. Researchers hypothesize that the severity of the disease is directly related to which of these phenotypes is responsible for the disease. Early onset Type 2 sufferers are more prone to premature aging of the cardiovascular system. In addition, early onset patients face an increased chance of developing hypertension, morbid obesity and an increased predisposition to the development of microalbuminuria, a risk factor for cardiovascular disease. Statistics have demonstrated that diabetes is the most significant cause of non-traumatic amputation in adult subjects (resulting from poor wound healing), and the leading ca
