What are the performance levels of the HPLC-Chip for small molecule applications?
Many small molecule applications benefit from the automated sample enrichment and direct injection workflow of the current HPLC-Chip design. We have achieved superior chromatographic performance and significantly enhanced sensitivity with the HPLC-Chip for several pharmaceutical and toxicology applications compared to conventional nanospray techniques while maintaining the same robustness, reliability and ease of use advantages. • Can I put this HPLC-Chip interface on my non-Agilent mass spectrometer? Agilent developed the HPLC-Chip using our LC/MSD Trap mass spectrometer and 1100 Series Nanoflow LC System for MS. The HPLC-Chip interface is available for this system and can be added to existing older Agilent Ion Traps. The HPLC-Chip interface is also available for the Agilent LC/MSD TOF and will be available for the Agilent LC/MSD (quadrupole) and the new Agilent QTOF in 2006. We are investigating the feasibility of using the HPLC-Chip interface for use with other types of MS instrumen
