What are the neural tube defects and their severity?
2.c The two main defects are spina bifida (open spine) and anencephaly. The problems associated with spina bifida will vary with the size, location and nature of the opening in the spine. Problems range from mild backaches to severe mental retardation, paralysis, bowel and bladder control problems and leg deformities. Generally speaking, the AFP test is more likely to detect the more severe forms of spina bifida. Anencephaly is a failure of the brain and skull to fully develop. It is incompatible with life.
