What are the molecular mechanisms involved in the perception, interpretation and transduction of those signals?
We are interested in understanding the molecular mechanism by which light regulates gene expression in plants. Our research program is focused on the phytochromes, the major and best-characterized family of plant regulatory photoreceptors. The photoreceptor molecule functions as a biological switch that, upon perception of the light signal, triggers changes in transcription which are detectable within 5 minutes of the stimulus. The general strategy we have adopted toward this problem is fourfold: • to examine the phytochrome molecule for clues to its photosensory function and mechanism of action using structural analysis, phytochrome-defective mutants and overexpression of mutagenized phytochromes in transgenic Arabidopsis. • to study genes under phytochrome control to identify promoter DNA elements and transcription factors involved in induction or repression of expression. • to identify signal transduction pathway components between the photoreceptor and the genes it regulates using
We are interested in understanding the molecular mechanism by which light regulates gene expression in plants. Our research program is focused on the phytochromes (phys), the red/far-red light-absorbing family of plant regulatory photoreceptors. The photoreceptor molecule functions as a biological switch that, upon perception of the light signal, triggers changes in transcription which are detectable within 5 minutes of the stimulus. The general strategy we have adopted toward this problem is fourfold: • To examine the phytochrome molecule for clues to its photosensory function and mechanism of action using structural analysis, phytochrome-defective mutants and overexpression of mutagenized phytochromes in transgenic Arabidopsis. • To study genes under phytochrome control to identify promoter DNA elements and transcription factors involved in induction or repression of expression. • To identify signal transduction pathway components between the photoreceptor and the genes it regulates
Related Questions
- The disease mechanism involved in familial hypercholesterolemia is BEST described as which of the following disease mechanisms?
- What are the molecular mechanisms involved in the perception, interpretation and transduction of those signals?
- What cellular changes and molecular signals underlie changes in TSC number?
