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What are the latest recommendations for measuring potencies of high purity factor VIII concentrates?

April 26, 2017concentrates Factor high latest measuring potencies purity recommendations VIII

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What are the latest recommendations for measuring potencies of high purity factor VIII concentrates?

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A concentrate standard should be used in lieu of plasma standards. b) Sample and standard concentrates should be pre-diluted in Factor VIII deficient plasma c) All assay buffers should contain 1% (10 mg/ml) of high purity albumin, either bovine or human. d) The chromogenic method is the reference method.