What are the indications for embryo biopsy for PGD?
• Carriers of single gene disorders. These patients benefit from PGD by reducing the risk of conceiving an affected baby. • Recurrent Miscarriage Fertile couples with repeated miscarriages should be evaluated for the presence of a chromosomal abnormality. The female or male partner may be a carrier of a balanced translocation or be an aneuploid mosaic. • Unsuccessful IVF cycles Couples with repeated unsuccessful IVF cycles should be evaluated for the presence of a chromosome abnormality. The female or male partner may be a carrier of a balanced translocation or be an aneuploid mosaic. • Unexplained Infertility The most probable cause of unexplained infertility or history of habitual miscarriage is a chromosome abnormality. The male OR female partner may be a carrier of a translocation or be an aneuploid mosaic. • Aneuploidy and Advanced Maternal Age Women of advanced maternal age (> 35) are at a higher risk of producing aneuploid embryos, resulting in implantation failure, a higher ris
