What are the hematocrit or hemoglobin values for the initiation of EPO?
The levels depend on the clinical indication for use of the ESA. Please see the appropriate coverage document for details on the specific indication of interest: for those uses related to cancer chemotherapy, see the NCD; the other reference you will need is the LCD. References: CMS Publication, IOM 100-03, Medicare National Coverage Determinations (NCD) Manual, Transmittal No. 80, Change Request #5818, January 14, 2008, describes the NCD for the use of ESAs in Cancer and Related Neoplastic Conditions.