What are the GFR changes with age?
The GFR declines with aging. Although the age-related decline in GFR has been considered part of normal aging, decreased GFR in the elderly is an independent predictor of adverse outcomes, such as death and CVD. In addition, decreased GFR in the elderly requires adjustment in drug dosages, as in other patients with CKD. Table 1 shows the average values of estimated GFR by decade in the general population, based on a small study of man.
