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What are the events that lead to pain due to disc degeneration?

degeneration Disc events lead pain
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What are the events that lead to pain due to disc degeneration?

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Cascade of events: Pain fibers have been identified in the discs and joints and ligaments of the spine using neuropeptide stains and sodium channel markers (see next paragraph). Discs degenerate due to environmental and genetic factors leading to poor disc rehydration and nutrient diffusion.

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