What are the effects LSD have on the brain?
In the beginning stages of onset, LSD is likely to cause a sort of undefineably feeling similar to anticipation or anxiety. There is often a slight feeling of energy in the body, an extra twinkle to lights, or the feeling that things are somehow different than usual. As the effects become stronger, a wide variety of perceptual changes may occur; non-specific mental and physical stimulation, pupil dilation, closed and open eye patterning and visuals, changed thought patterns, feelings of insight, confusion, or paranoia, and quickly changing emotions (happiness, fear, gidiness, anxiety, anger, joy, irritation) The effects of LSD are attributed to its strong partial agonist effects at 5-HT2A serotonin receptors as specific 5-HT2A agonist drugs are also psychedelics erowid.
