What are the differences between the roles of the National Center for Biotechnology Information (NCBI) and the Coordinating Center?
NCBI will receive, link, store and distribute individual-level data for study subjects provided by Study Investigators and the genotypes produced by the genotyping facilities. NCBI will provide the study genotype-phenotype dataset to Study Investigators and all others whose requests are approved by the Data Access Committee. NCBI will also perform basic genotype-phenotype correlations, the results of which will be provided through NCBI’s Web site. Study Investigators and the Coordinating Center will be responsible for conducting statistical analyses for individual studies and across studies, respectively. (See: What is the Coordinating Center’s role …). If appropriate, the Coordinating Center will send updated or newly created data (e.g., new variables created as part of a data harmonization effort) to NCBI.
