What are the differences between CellSpray and traditional Epithelial Autografts?
Cultured Epithelial Autograft (CEA) sheets have been commercially available for over two decades. Despite its availability, the lengthy culture process, the difficulty applying sheets and the high costs associated with its production and application has significantly limited CEA use. CEA sheets can take up to 3 weeks to produce and require extensive application time as they are generally supplied in small sheets (50cm2) and are fragile and difficult to apply. CEA sheets are produced with varying product quality, in terms of cell yield and viability and are associated with poor take when applied to high contour and high sheer areas(ii). CellSpray is cultured as pre-confluent keratinocytes and supplied in a suspension form. CellSpray can be cultured in a few days, using a site-matched biopsy the fraction of the size of a traditional skin graft. As CellSpray can be applied earlier than traditional CEA sheets and have high numbers of viable cells, increased epithelialisation and reduced sc
