What are the definitions for roles in Biomarkers Knowledge Area?
Diagnosis: The role of this biomarker is to identify or detect a disease. Differential Diagnosis: The role of this biomarker is to distinguish between two or more diseases with similar signs and symptoms. Monitoring Treatment Efficacy: The role of this biomarker is to identify signs of a change (usually beneficial) as a result of treatment. A biomarker used for monitoring treatment efficacy is usually measured before the treatment starts (baseline) and at stages throughout the treatment (follow up). Monitoring Treatment Toxicity: The role of this biomarker is to identify signs of adverse effects as a result of treatment. Measured at baseline and at stages throughout treatment. Prediction of Drug Resistance: The role of this biomarker is to detect possible resistance to a therapy and thus to exclude that therapy from the possible therapies available to the patient. Predicting Treatment Efficacy: The role of this biomarker is to predict a probable beneficial outcome as a result of treatm
