What are the contraindications to Depo-Provera?
There are no absolute contraindications to Depo-Provera other than known or suspected pregnancy and the presence of undiagnosed vaginal bleeding. The use of anticoagulants necessitates special care to avoid hematoma with intramuscular injection. Past severe arterial disease, severe hepatic disease with markedly abnormal liver function, acute porphyria, recent trophoblastic disease (until hCG is undetectable) and rare hypersensitivities to the constituents of Depo-Provera are also considered contraindications to Depo-Provera use.
