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What Are the Common Side Effects of Adjuvant Hormonal Therapy for Breast Cancer?

April 26, 2017adjuvant breast cancer common hormonal saskatoon therapy undergraduate university of saskatchewan

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What Are the Common Side Effects of Adjuvant Hormonal Therapy for Breast Cancer?

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You may consider answering the following multiple choice questions before reading the information provided. The answers are given at the bottom of the page. Q1: All of the following regarding aromatase inhibitors are correct except 1. Unlike tamoxifen, AI’s are associated with an increased risk of endometrial cancer. 2. AI’s have been shown to reduce bone density, and increase the risk of fractures. 3. Aromatase inhibitors are not indicated in premenopausal women. 4. The musculoskeletal symptoms associated with the AI’s are transient. Q2: Which of the following statements regarding tamoxifen is correct? 1. Compared with AI’s, tamoxifen has been associated with a decreased risk of venous thromboembolic events. 2. Similar to AI’s in post menopausal women tamoxifen increases the risk of bone loss and osteoporosis. 3. In post menopausal women tamoxifen has shown better efficacy than inhibitors. 4. Tamoxifen may be associated with an increased risk of ischemic cereborvascular complications.