What are the characteristics of an effective HIV microbicide?
• Be active against a range of STDs, as well as HIV. Ideally, a microbicide would work against all STDs (syphilis, warts, herpes, chlamydia, gonorrhea, HPV, Hepatitis B) but this would be difficult to achieve since STDs can be either bacterial or viral. • Not irritate the rectal and vaginal tissue (Nonoxydol-9, a spermicide which is still available in some personal lubricants, was found to irritate the rectal lining, increasing the possibility of HIV transmission.) • Be available, with and without spermicidal agents that prevent pregnancy • Stay effective over a long period of time. • Be acceptable and easy to use. • Remain stable at high temperatures. • Not be absorbed into the rest of the body, meaning that it would remain in the rectal or vaginal cavity. Return to top. How can I get involved in the search for an HIV microbicide? If you are interested in volunteering for a microbicide study, please contact AIDS Research Alliance at 310/358-2429, or email us at microbicides@aidsresear
