what are the chances of neural tube defects at 33yrs and slightly high AFP?
1) Maternal age is not a risk factor for neural tube defects. 2) It depends on how high the AFP is how high the neural tube defect risk is. If it is truly “slightly high” it is most likely less than a 5% chance of neural tube defect. 3) It depends on if you have already had a normal high resolution ultrasound (which can see 90-95% of neural tube defects).
