What are the chances of inheriting Sickle Cell?
A12: If one parent has Sickle Cell Trait and the other has all normal hemoglobin, for each pregnancy there is a 50 percent chance the child will have all “AA” hemoglobin and a 50 percent chance the child will have “AS” or another Sickle Cell Trait type. If both parents have Sickle Cell Trait, for each pregnancy there is a 1 in 4 chance the child will have Sickle Cell Disease, and a 1 in 4 chance the child will have all normal hemoglobin, and a 2 in 4 chance the child will have “AS” or another Sickle Cell Trait type. Persons with SC hemoglobin sometimes experience the same symptoms as persons with Sickle Cell anemia, although the symptoms may not be as severe. Approximately 1 out of every 1,000 black Americans has Sickle Cell-Hemoglobin C Disease.
