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What are the causes of smear positive specimen negative on culture?

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What are the causes of smear positive specimen negative on culture?

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Ans: (i) False positive smear result (ii) Bacilli might have lost ability to grow in culture due to the following reasons: – Bacilli killed or harmed by treatment – Exposure to heat and sunlight – Long storage of sputum specimen – Excessive decontamination procedures while processing the specimen for culture

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