What are the causes of Low cortisol hormone??
The disease of low cortisol production can arise either because of destruction of adrenal gland itself (Addison’s disease or primary hypocortisolism) or due to malfunction of pituitary or hypothalamus (secondary hypocortisolism). Common causes of secondary adrenal insufficiency are tumors of the pituitary, head injury, radiotherapy and long standing steroid medication suppressing the axis. The primary adrenal deficiency, also called Addison’s disease, is the result of infective or inflammatory or infiltrative processes involving the adrenal glands. The most common is the autoimmune destruction of the glands. This is followed by less commoner conditions like metastasis, amyloidosis, tuberculosis, opportunistic infection in AIDS/HIV, infarction, haemorrhage, adrenomyeloneuropathy, congenital adrenal hyperplasia etc. What are the clinical features of Addison’s disease? Symptoms are non-specific. Common presentations are loss of weight, loss of appetite, tiredness, hyper-pigmentation of th
