What are the causes of Crohns Disease?
Nobody is entirely sure because no theory has been proven. It is most likely due to an abnormality in the person’s immune system, by mistaking bacteria, foods and some other substances as foreign invaders, and attacking them. This action causes a massive increase in the number of white blood cells that accumulate in the lining of the intestines – leading to chronic inflammation, followed by ulcerations and bowel injury. We do not know whether this action by the immune system is the cause or the result of the disease. Scientists say there are three factors which bring about inflammation in the GI tract of people with Crohn’s Disease: — The patient’s genes — The patient’s immune system — The environment Antigens, or foreign substances, are present in the environment. Perhaps the immune system’s reaction to these antigens, or maybe the antigens themselves, cause the inflammation. The immune system produces a protein called tumor Necrosis Factor (TNF) – perhaps the protein causes the in