What are the Causes of an Enlarged Liver and Spleen?
That brings us back to enlarged liver and spleen causes. As we mentioned earlier, hepatosplenomegaly is treated more as a symptom than a disorder, as it is caused due to some underlying factor affecting the smooth function of kidney, liver and red blood cells in the body. There are hundreds of medical conditions, any one of which can result in spleen and liver enlargement at the same time. While most of these are very rare conditions, others are common such as cancer, hepatitis C, leukemia etc. Among the major reasons for an enlarged liver and spleen, viral liver infections are by far the most common. Such infections include hepatitis C, cirrhosis of the liver, typhoid, etc. While many people are aware of the fact that excessive consumption of alcohol causes disorders like liver cirrhosis which causes the spleen and liver to enlarge, not many of them know that non-alcoholic fatty liver disease, which results in fat accumulation and inflammation in the liver, can also result in the same