What are the appropriate biosafety practices and containment conditions for work with this agent?
The “Interim CDC-NIH Recommendation for Raising the Biosafety Level for Laboratory Work Involving Noncontemporary Human Influenza Viruses” (http://www.cdc.gov/flu/h2n2bsl3.htm) excerpted from the draft CDC/NIH “Biosafety in Microbiological and Biomedical Laboratories,” 5th edition will be used as the minimum containment for such experiments. However, in some cases supplemental biosafety measures may be deemed appropriate after review of the proposed experiments by CDC DSAT. The CDC DSAT will review the entity’s biosafety plan to ensure that it provides a comprehensive risk assessment of the proposed research and adequately ensures appropriate biosafety measures. The case-by-case review will continue until further data are available that may result in changes to biosafety guidelines for work with the reconstructed 1918 pandemic influenza virus.
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