What are the applications of the WHQ?
The WHQ is widely used to assess health related QOL in samples of healthy women and in those seeking help for specific physical or emotional problems. It has been used in a series of cross-sectional and prospective studies of mid-aged women by the author and co-workers [4,9,18]. However, the main application has been the evaluation of the efficacy of medical and non-medical interventions for specific symptoms and upon health related quality of life. The WHQ has been and is currently being used in a number of national and multinational clinical trials of hormonal preparations for menopausal and postmenopausal women [11-13,19-28]. For example, in the U.K. the WHQ has been included in the WISDOM trial as part of a detailed evaluation of quality of life changes following hormonal treatment [19]. The scale is also being used to evaluate the effects of hormone replacement therapy in a large randomised controlled trial of breast cancer patients in the U.K., as well as in a study of the impact