What are the applications for ColCount?
ColCount is specifically aimed at scientists and technicians utilising the clonogenic cell-survival (or colony-forming) assay to quantify the fraction of plated mammalian cells surviving a given drug, radiation or other treatment regime. Typical applications for ColCount include: Radiation research, Chemotherapy research, Drug development, Drug Screening, Toxicology, Pharmacology. A cell is deemed to have survived if it is capable of division and colony formation. Commonly, this involves transformed cell-lines that grow on solid surfaces such as Petri dishes. In some instances, colonies are grown in semi-solid matrices such as methylcellulose or soft agar (see below).