WHAT ARE THE ADVERSE RISKS THAT HAVE OCCURRED TO PEOPLE TAKING VALPROATE?
Taking this drug during the first three months of pregnancy resulted in more birth defects and increased the chance that the child would have impaired cognitive development. We don’t know how use of this drug increased these problems. It remains an area that needs more research. WERE THERE OTHER RISKS FOR WOMEN WITH EPILEPSY? It was interesting that there were not many increased risks for obstetrical outcomes, including C-sections. We didn’t find an increased risk for premature labor and delivery – there were a lot of reassuring outcomes. IS THERE ANYTHING THAT WOMEN WITH EPILEPSY NEED TO WATCH DURING PREGNANCY? Some changes occur with pregnancy, the most significant being that blood levels of the drug decline. Medicines clear through the kidneys more efficiently and the blood levels decline, so that could increase the risk of having a seizure. Women need to work with their physicians to have blood levels checked frequently. WERE THERE ANY CHANGES IN OTHER MEDICATIONS THAT RAISED RED F
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