What are the advantages of Silicon-Carbon bonding for stationary phases? How will that benefit me?
[top] Typical HPLC phases today are made with siloxane (Si-O-Si-C) bonds which are prone to hydrolysis. Silicon-Carbon bonds are much more stable and resistant to hydrolysis and is therefore less phase bleed-off. This means that these columns will last longer and be more rugged and will be reproducible longer. This also means that you might be able to explore new mobile phase/additive and temperature conditions to achieve very difficult separations that might be impossible with your current HPLC columns. Also, standard type B columns made with silanization of organo-silanes to produce siloxane bonded ligands limits the phases which may be bonded onto silica. With our patented, silica-hydride surface many compounds previous thought to be improbable to bond to silica can be easily bonded. Examples of this is our unique UDC-Cholesterol , plus our unique ability to custom synthesis novel phases for our customers.
