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What are the advantages of PEGylation of peptides?

April 26, 2017advantages pegylation peptides

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What are the advantages of PEGylation of peptides?

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PEGylation adds poly (ethylene glycol) polymer to target molecules through covalent attachments. PEGylation effectively enhances the peptides therapeutic properties by masking them from the hosts immune system, increasing their solubility (for hydrophobic drugs) and bioavailability. It can also prolong the peptides circulatory time within the host through reduced renal clearance.