What are the advantages of ENU mutagenesis and phenotypic screening?
Multiple types of mutations (hypermorph, hypomorph, neomorph) Induce allelic series Potential to avoid null (knock-out) lethality Induces single base-pair substitutions, i.e. “point mutations” Create novel phenotypes Identify previously unknown gene functions Please also check out our SFN 2004 functional genomics poster.
