What are the advantages of Aspers technology?
Simplicity o Four color detection system; all four possible sequence variants are detected in the same reaction; o Low reagent complexity – oligonucleotides, dye terminators, DNA polymerase and DNA sample. o Robust and durable detection system High quality and accuracy o Excellent power of allelic discrimination o Two- step biological quality control – hybridization and primer extension o Parallel SNP detection on both DNA strands additional internal control at negligible extra cost o High specificity, sensitivity and reproducibility Fast and high throughput o time required for the complete APEX reaction is less than an hour, several APEX reactions can be carried out in parallel with minimal effort. o From 1 to thousands of SNPs per assay o As the chip production is based on printing, it is highly parallel and less time consuming than in situ synthesis. Cost-effective o Low initial investment o Low running costs o No need for expensive optically flat polished slides o One oligo per SNP
