What are some other research findings in RTT?
• Autonomic Findings • Disorganized breathing • Vasomotor changes (blue hands and feet) • Vacant spells • Constipation 90% • Abdominal distention (bloating) 50% • Biochemical Findings • Elevated levels of beta-endorphins in cerebrospinal fluid (CSF) • Decreased levels of dopamine & norepinephrine metabolites in (CSF) • Cardiovascular Findings • Prolonged QT syndrome • Immaturity of the atrio-ventricular conduction system (heart) • Nutritional Findings • Growth failure has many causes, but has a strong basis in nutritional deficit. • Progressive weight and height failure despite aggressive nutritional rehabilitation. • Repetitive involuntary motor movements are not associated with increased energy expenditure. • Sleeping metabolic rates are low and are consistent with features of malnutrition; these findings can be reversed with nutritional support • Deficits in lean body mass persist despite aggressive refeeding regimens. • Deficits in lean body mass may be associated with increased ra
