What are some other major knowledge gaps?
Y.G.: Every year we meet many reassorted viruses, we don’t know which can jump to humans. Which one could become a pandemic? Nobody knows. We lack the knowledge to distinguish which virus has pandemic potential. This is a big limitation. Many of us influenza researchers, we blame ourselves; if we have this knowledge, then we can get rid of pandemics in human beings. Life becomes very meaningful if you do something like that. SARS has been averted for 6 years. But I’ve been working 20 years on flu. I still don’t know which variant will cause a pandemic. I feel frustrated by this. In my lifetime, I won’t be able to solve this. Hopefully, my students will. Q: Are you surprised there hasn’t been a SARS outbreak since 2003? Y.G.: The ecosystem was disrupted. No more large amounts of wild animals in the market, just next to your door. It was like a big mixing vessel. Like a PCR [polymerase chain reaction] machine. Put the virus in and amplify it. That’s why my group has worked so hard to stu
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