What are some of the systemic diseases that have oral signs?
CW: Many endocrine problems can cause changes in the eruption schedule of children. Usually the “hypo” conditions result in delayed exfoliation and eruption and the “hyper” conditions result in accelerated exfoliation and eruption. For example, untreated hypothyroidism will lead to delay in eruption of primary teeth, delay in exfoliation of these teeth and subsequent delay in the eruption of the permanent teeth. Whereas, hyperpituitarism can result in early eruption and exfoliation of the primary teeth and early eruption of the permanent teeth. Most congenital syndromes have some dental involvement. Children with Down syndrome usually have delayed eruption and are prone to periodontal problems. Achondroplastic dwarfs have enamel defects and delayed eruption and exfoliation. Other systemic diseases with oral manifestations are leukemia, vitamin D resistant rickets, diabetes, and histiocytosis. Still more diseases may not cause oral manifestations themselves but the treatment may, such a
