What are some of the symptoms of disease outside the GI tract?
Those affected with celiac disease do not always show common gastrointestinal symptoms of the disease, such as diarrhea or abdominal cramping and bloating. In fact, they may experience extra-intestinal symptoms, or problems outside of the intestine, that can involve many of the body’s different organs and systems. Extra-intestinal Symptoms (not all inclusive): Blood • Improper absorption of vitamin K (a fat soluble vitamin) can result in bleeding problems • Anemia due to insufficient absorption of folate and iron in the small intestine, as well as chronic mild blood loss; in severe cases of sprue, a deficiency of B12 can also lead to anemia Bone • Osteoporosis / Osteopenia [decrease in the amount of bone tissue] These conditions result from insufficient absorption of calcium and vitamin D by the damaged intestinal villi, as well as due to inflammatory processes directly targeting bone. • Joint Pain/Bone Pain Neurologic • Neurological symptoms include muscle weakness, numbness, and atax
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