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What are some complications of sickle cell disease?

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What are some complications of sickle cell disease?

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• Anemia (low red blood cell count) • Hand and Foot Syndrome – Painful swelling in the hands and feet. • Severe Infections – Sepsis (blood stream infection), meningitis, and pneumonia. The risk of infection is increased because the spleen does not function properly. • Splenic Sequestration Episodes – The spleen is the organ that filters blood. Rapid enlargement can result due to trapping of sickled cells in the spleen. This condition can be life threatening. • Stroke – Occurs when sickled cells create a blockage of blood flow within the brain. Signs include seizure, weakness in the arms and legs, speech problems, and loss of consciousness. • Acute Chest Syndrome – A serious condition caused by infection or trapped red blood cells in the lungs.

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