What are serotonin norepinephrine reuptake inhibitors (SNRIs)?
SNRIs are the newest class of antidepressants. SNRIs work by increasing the levels of serotonin and norepinephrine in the brain. Drug interactions and side effects associated with SNRIs are similar to those seen with SSRIs. SNRIs may increase blood pressure, especially at high doses. High blood pressure caused by SNRIs may be managed by reducing the dose of the SNRI. What are examples of SNRIs? • duloxetine (Cymbalta) • venlafaxine (Effexor) • desvenlafaxine (Pristiq) Conclusion Depression is a serious condition that often can be effectively treated with available therapies. Many antidepressants have been developed over the years. The newer classes of antidepressants are better tolerated and associated with fewer drug interactions than the older class of antidepressants. Side effects and drug interactions are barriers to successful treatment. Some side effects of antidepressants resolve with continued use while other side effects can be managed by dose reduction or adding other therapi
