What are prostaglandin inhibitors?
Prostaglandin inhibitors block your body’s production of prostaglandins. Prostaglandins are chemical substances that make your uterus contract more strongly during your period. Prostaglandin inhibitors can help ease the headache, and general aches and pains (such as cramps) that some women have with PMS. Prostaglandin inhibitors include naproxen (brand names: Anaprox, Naprosyn) and mefenamic acid (brand name: Ponstel). They’re usually taken right before and during the beginning of your period. Do antidepressants help? Antidepressants and medicine to treat anxiety can help with the severe irritability, depression and anxiety that some women with PMS have. These medicines are usually only taken during the time you would normally have these symptoms. What other medicines are there? Bromocriptine mesylate (brand name: Parlodel) may help prevent breast pain. Studies are still being done about using bromocriptine this way. Studies are also being done about using hormones to treat PMS symptom