What are other important factors when determining prognosis?
Besides histology, there are other factors that are important when determining prognostic significance. Of course, the age at diagnosis is important, with children under the age of 1 year having the best overall prognosis. Here are some other important factors: neuron-specific enolase: normal level (1- 100 ng/ml) > abnormal (> 100 ng/ml) ferritin level: normal level (0- 150 ng/ml) > abnormal (> 150 ng/ml) VMA/HVA ratio: high (> 1) > low (< 1) stage: I or II or IVs > III > IV site of primary tumor: neck/ posterior mediastinum/ pelvis > abdominal primaries gallium uptake by tumor: absent > present n-myc amplification: 1 n-myc copy > greater than 1 n-myc copy P-glycoprotein levels in tumor cells at dx: expression before treatment may be of some prognostic significance. expression of neural growth factor receptor (TRK) gene: high levels of messenger RNA of TRK gene in tumor cells strongly predicts good outcome. lower LDH levels (< 1500 u/ml) > high LDH levels (> 1500 u/ml) Ha-ras p21 expre
