What are mucopolysaccharide diseases (MPS)?
MPS, also known as lysosomal storage diseases, are rare, life-threatening, progressive metabolic conditions each caused by a shortage of a particular enzyme. The enzyme deficiency that results from mucopolysaccharide diseases means the body can’t break down (metabolise) certain molecules called GAGs (glycosaminoglycans). GAGs are structural molecules that are integral to connective tissues such as cartilage. They accumulate in cells within tiny structures called lysosomes. This leads to dysfunction the cells, resulting in dysfunction of tissues and organs. There are many different types of MPS including: Hurler; Hunter; Sanfillipo; Morquio; Maroteaus-Lamy and Sly.
